Lots of hedging there. :-)
Sure, there might be big surprises yet to come. Science is inherently falsifiable.
But science can't be infinite. At some point our understanding of the physical sciences will be mature - no significant breakthroughs will follow.
Thinking purely technologically, how many people's jobs depend on technology which requires fundamental science discovered since 1950? How much depends on fundamental science discovered between 1880 and 1950?
There really haven't been any fundamental breakthroughs since the Standard Model ending around 1980, and even that didn't open up any possibilities for new technology.
All this points to a science that is approaching maturity.
In my lifetime, we mapped the entire surface of the Earth. There are no doubt hidden areas, and the bottom of the sea is unknown, but Shangri-La cannot exist.
I hate to break it to you, but it might be that our view of the universe isn't going to change very much in the future. The speed of light might be an absolute barrier, there might well be no magical new forms of energy, and the only way to go forward is with hard work and more or less the science we have today.
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As for the nationalistic policy - preach, brother.
We should be throwing every penny we can spare toward fusion power, and getting off fossil fuels entirely. Instead, the US spends trillions on imaginary enemies while losing every actual war it starts.